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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
CN
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主要文件

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安全信息

906883

Sigma-Aldrich

Decellularized ECM bioink precursor

from porcine bone, suitable for 3D bioprinting applications

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About This Item

表单

semisolid

组成

Collagen (hydroxyproline), 60-120 μg/mg
GAG (bicolor), 1.5-5.0 μg/mg

颜色

white to beige

储存温度

−20°C

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应用

The extracellular matrix (ECM), comprised of proteins and other growth factors, plays a pivotal role in directing and mediating cellular activities in a tissue or an organ. Decellularized extracellular matrix (dECM) could not only replicate natural ECM microenvironment, but also provide tissue specific compositions and topology. dECM bioink is capable of providing optimized tissue-specific microenvironment conducive to the growth of 3D structured tissues.
Decellularized ECM bioink precursor is provided as an aseptic form. Reconstitution protocol is provided to prepare dECM bioink solution. The final bioink is used for bioprinting self-supporting 3D structures.

法律信息

Product of T&R Biofab

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    MKCR1385
    MKCL0887

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    Geunseon Ahn et al.
    Scientific reports, 7(1), 8624-8624 (2017-08-19)
    Three-dimensional (3D) cell printing systems allow the controlled and precise deposition of multiple cells in 3D constructs. Hydrogel materials have been used extensively as printable bioinks owing to their ability to safely encapsulate living cells. However, hydrogel-based bioinks have drawbacks
    Deepak Choudhury et al.
    Trends in biotechnology, 36(8), 787-805 (2018-04-22)
    The extracellular matrix (ECM) comprises a complex milieu of proteins and other growth factors that provide mechanical, biophysical, and biochemical cues to cells. The ECM is organ specific, and its detailed composition varies across organs. Bioinks are material formulations and
    Byoung Soo Kim et al.
    Biomaterials, 168, 38-53 (2018-04-04)
    3D cell-printing technique has been under spotlight as an appealing biofabrication platform due to its ability to precisely pattern living cells in pre-defined spatial locations. In skin tissue engineering, a major remaining challenge is to seek for a suitable source
    Falguni Pati et al.
    Nature communications, 5, 3935-3935 (2014-06-03)
    The ability to print and pattern all the components that make up a tissue (cells and matrix materials) in three dimensions to generate structures similar to tissues is an exciting prospect of bioprinting. However, the majority of the matrix materials

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