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Merck
CN
所有图片(1)

文件

808350

Sigma-Aldrich

TokeOni

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所有图片(1)
别名:
2-[（1,3）-4-[4-（二甲氨基）苯基]-1,3-丁二烯-1-基]-4,5-二氢-（4）-4-噻唑羧酸盐酸盐, AkaLumine-HCl, 可溶性近红外发射荧光素
经验公式（希尔记法）:
C16H19ClN2O2S · xHCl
分子量:
338.85 (free base basis)
UNSPSC代码:
12352103
PubChem化学物质编号:
329769097
NACRES:
NA.23

形式

powder

质量水平

100

储存温度

−20°C

SMILES字符串

CN(C)C1=CC=C(/C=C/C=C/C2=N[C@@H](C(O)=O)CS2)C=C1.[H]Cl

InChI

1S/C16H18N2O2S.ClH/c1-18(2)13-9-7-12(8-10-13)5-3-4-6-15-17-14(11-21-15)16(19)20;/h3-10,14H,11H2,1-2H3,(H,19,20);1H/b5-3+,6-4+;/t14-;/m1./s1

InChI key

PZCNKVAGZCXXHX-SSRSOBHISA-N

相关类别

一般描述

  • 荧光素是在产生生物发光的生物体中发现的发光化合物的通称。
  • TokeOni是一种新的近红外发射荧光素类似物，发光峰在670 ~ 680 nm，峰值范围在近红外区。
  • TokeOni has the enhanced solubility of >10 mg/mL compared to HCl free (0.2 mg/mL).

应用

  • 生物成像。
  • 体内成像。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Synthesis and luminescence properties of biphenyl-type firefly luciferin analogs with a new, near-infrared light-emitting bioluminophore.
Chihiro M, et al.
Tetrahedron, 69(46), 9726-9734 (2013)
Development of simple firefly luciferin analogs emitting blue, green, red and near-infrared biological window light.
Satoshi I, et al.
Tetrahedron, 69(19), 3847-3856 (2013)
Gi Bum Kim et al.
Cell, 179(1), 251-267 (2019-09-21)
In situ transgenesis methods such as viruses and electroporation can rapidly create somatic transgenic mice but lack control over copy number, zygosity, and locus specificity. Here we establish mosaic analysis by dual recombinase-mediated cassette exchange (MADR), which permits stable labeling

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