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Merck
CN

753009

Sigma-Aldrich

SPho Pd G2

别名:

SPhos-Pd-G2, 氯(2-二环己基膦-2′,6′-二甲氧基-1,1′-联苯)[2-(2′-氨基-1,1′-联苯)] 钯(II), 第二代 SPhos 预催化剂

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About This Item

经验公式(希尔记法):
C38H45ClNO2PPd
分子量:
720.62
MDL编号:
UNSPSC代码:
12161600
PubChem化学物质编号:
NACRES:
NA.22

形式

solid

质量水平

特点

generation 2

反应适用性

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings

mp

218 °C (dec.)

官能团

phosphine

SMILES字符串

COC1=CC=CC(OC)=C1C2=C(P(C3CCCCC3)C4CCCCC4)C=CC=C2.NC5=C(C6=C([Pd]Cl)C=CC=C6)C=CC=C5

InChI

1S/C26H35O2P.C12H10N.ClH.Pd/c1-27-23-17-11-18-24(28-2)26(23)22-16-9-10-19-25(22)29(20-12-5-3-6-13-20)21-14-7-4-8-15-21;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;;/h9-11,16-21H,3-8,12-15H2,1-2H3;1-6,8-9H,13H2;1H;/q;;;+1/p-1

InChI key

NOMWEFBAPVZIIP-UHFFFAOYSA-M

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一般描述

SPhos Pd G2 是第二代 (G2) 预催化剂,其中 (G1) 复合物的苯乙胺主链被联苯基配体取代。与上一代产品相比,其允许在室温下用弱磷酸盐或碳酸盐碱制备活性钯化合物。这种催化剂被证明非常善于在其它交叉偶联反应中实现各种 Suzuki-Miyaura 偶联。

应用

在 Suzuki-Miyaura 偶联反应中的应用:
  • 1-烷基-3-溴-2-苯基-2,1-硼杂萘的自芳基化生成 2,1-硼杂萘二酚。
  • Ru (bpy) 2] + 与 4-羧基苯硼酸的 Suzuki–Miyaura 偶联。
  • Suzuki–Miyaura 偶联-硼化卟啉与 2-碘苯胺。

相关产品

产品编号
说明
价格

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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Modular synthesis of simple cycloruthenated complexes with state-of-the-art performance in p-type DSCs
Brunner F, et al.
Journal of Material Chemistry C, 4(41), 9823-9833 (2016)
Accessing 2, 1-Borazaronaphthols: Self-Arylation of 1-Alkyl-2-aryl-3-bromo-2, 1-borazaronaphthalenes
Molander, Gary A and Wisniewski, Steven R
The Journal of Organic Chemistry, 79(17), 8339-8347 (2014)
Pictet-Spengler Synthesis of Quinoline-Fused Porphyrins and Phenanthroline-Fused Diporphyrins
Gao K, et al.
Angewandte Chemie (International Edition in English), 55(42), 13038-13042 (2016)

商品

All of the preformed catalysts used in the kit are air and moisture stable complexes in their commercially available form.

Tools aid in kit setup for organic chemistry techniques, ensuring ease and success.

Materials Included in your KITALYSIS-24PD-2PK High-Throughput Screening Kit

Preformed catalysts in the kit are stable but become air-sensitive when activated; Schlenk technique aids scale-up.

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