跳转至内容
Merck
CN

745979

tbuttphos Pd G3

96%, solid

别名:

叔 -BuBrettPhos-Pd-G3, [（2-二-叔-丁基膦-3,6-二甲氧基-2′,4′,6′-三异丙基-1,1′-联苯）-2-（2′-氨基-1,1′-联苯）] 甲磺酸钯 (II)

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C44H62NO5PPdS
化学文摘社编号:
1536473-72-9
分子量:
854.43
UNSPSC Code:
12161600
PubChem Substance ID:
329765730
NACRES:
NA.22
MDL number:
MFCD25976528

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

tbuttphos Pd G3, 96%

SMILES string

COC1=CC=C(C(P(C(C)(C)C)C(C)(C)C)=C1C2=C(C=C(C=C2C(C)C)C(C)C)C(C)C)OC.NC3=C(C=CC=C3)C4=C(C=CC=C4)[Pd]OS(C)(=O)=O

InChI key

GAQPAUHHECNHNS-UHFFFAOYSA-M

InChI

1S/C31H49O2P.C12H10N.CH4O3S.Pd/c1-19(2)22-17-23(20(3)4)27(24(18-22)21(5)6)28-25(32-13)15-16-26(33-14)29(28)34(30(7,8)9)31(10,11)12;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;/h15-21H,1-14H3;1-6,8-9H,13H2;1H3,(H,2,3,4);/q;;;+1/p-1

assay

96%

form

solid

feature

generation 3

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings

mp

119-131 °C

functional group

phosphine

Quality Level

100

相关类别

Application

tBuBrettPhos Pd G3 已被用作在温和反应条件下氨基酸酯与芳基三氟甲磺酸酯的 N -芳基化的预催化剂，且氨基酸酯的消旋作用极小。它也可用于在苯甲醛肟作为氢氧化物替代物存在下催化芳基卤化物转化为酚类。

对于小规模和高通量应用，产品为 ChemBeads (928313)

General description

tBuBrettPhos Pd G3 是第三代 (G3) Buchwald 预催化剂，可用于交叉偶联反应，形成 C-C、C-N、C-O、C-F、C-CF3 和 C-S 键。它具有空气、水分和热稳定性，可溶于多种常见有机溶剂。它具有催化剂用量少、反应时间短、能有效地形成活性物种和精确控制配体钯比等特点。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000231418
SHBR5579
0000231418
0000193171
0000193171

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Hailey A Young et al.
The Journal of organic chemistry, 85(3), 1748-1755 (2019-12-04)
Palladium-catalyzed N-arylations of amino acid tert-butyl esters using 4-bromo-N,N-dimethylaniline as a coupling partner are reported. The resulting N-aryl amino acid esters are suitable building blocks for the synthesis of electron-rich N-aryl peptides, which undergo oxidative couplings to aminooxy groups to
Synthesis of Complex Phenols Enabled by a Rationally Designed Hydroxide Surrogate.
Fier PS & Maloney KM
Angewandte Chemie (International Edition in English), 56(16), 4478-4482 (2017)
Sandra M King et al.
Organic letters, 18(16), 4128-4131 (2016-08-09)
A general method for the N-arylation of amino acid esters with aryl triflates is described. Both α- and β-amino acid esters, including methyl, tert-butyl, and benzyl esters, are viable substrates. Reaction optimization was carried out by design of experiment (DOE)

商品

G3 and G4 Buchwald Precatalysts

G3 and G4 Buchwald palladium precatalysts are the newest air, moisture, and thermally stable crossing-coupling complexes used in bond formation for their versatility and high reactivity.

G3和G4 Buchwald预催化剂

G3和G4 Buchwald预催化剂是一类最新的空气、湿度和热稳定型交叉偶联复合物，可用于键形成以实现其多功能性和高反应性。

相关内容

Buchwald and non-Buchwald catalysts and ligands for pharma or industrial chemistry applications

Explore reliable, premium grade catalysis materials for your pharma or industrial project. Specialty chemicals and formulations are available in bulk quantities and volumes from a few grams to multi-metric tons with complete documentation to simplify your leap from development to commercialization.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持