74540
去甲二氢愈创木酸
≥97.0% (HPLC)
别名:
1,4-双(3,4-二羟苯基)-2,3-二甲基丁烷, 4,4′-(2,3-二甲基四亚甲基)二邻苯二酚, NDGA, 马索罗酚
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线性分子式:
[-CH(CH3)CH2C6H3-1,2-(OH)2]2
化学文摘社编号:
分子量:
302.36
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-903-0
Beilstein/REAXYS Number:
2056826
MDL number:
产品名称
去甲二氢愈创木酸, ≥97.0% (HPLC)
InChI
1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3
InChI key
HCZKYJDFEPMADG-UHFFFAOYSA-N
SMILES string
CC(Cc1ccc(O)c(O)c1)C(C)Cc2ccc(O)c(O)c2
assay
≥97.0% (HPLC)
form
crystals
impurities
≤2% water
mp
184-186 °C (lit.)
Quality Level
Gene Information
mouse ... Alox12(11684)
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Biochem/physiol Actions
脂氧合酶抑制剂；含多酚的邻二羟基（儿茶酚）结构。
Application
去甲二氢愈创木酸可用于：
- 具有高HIV抑制活性的去甲二氢愈创木酸衍生物的合成。
- 作为合成四-O-甲基去甲二氢愈创木酸的起始原料。
General description
去甲二氢愈创木酸（NDGA）可用作抗氧化剂和活性氧（ROS）的强效清除剂。
Other Notes
蚕豆脂氧合酶抑制剂
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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