跳转至内容
Merck
CN
所有图片(8)

主要文件

查看所有文档

741825

Sigma-Aldrich

XPhos Pd G2

98%

别名:

X-Phos氨基联苯氯化钯预制催化剂, XPhos-Pd-G2, 氯(2-二环己基膦基-2′,4′,6′-三异丙基-1,1′-联苯基)[2-(2′-氨基-1,1′-联苯)]钯(II), 第二代XPhos预制催化剂

登录查看公司和协议定价
所有图片(8)

About This Item

经验公式（希尔记法）:
C45H59ClNPPd
CAS号:
1310584-14-5
分子量:
786.80
UNSPSC代码:
12161600
PubChem化学物质编号:
329765534
NACRES:
NA.22

质量水平

100

方案

98%

表单

solid

特点

generation 2

反应适用性

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings

mp

202-210 °C

官能团

phosphine

SMILES字符串

Nc1ccccc1-c2ccccc2[Pd]Cl.Nc3ccccc3-c4ccccc4[Pd]Cl.CC(C)c5cc(C(C)C)c(-c6cccc(c6)P(C7CCCCC7)C8CCCCC8)c(c5)C(C)C.CC(C)c9cc(C(C)C)c(c(c9)C(C)C)-c%10ccccc%10P(C%11CCCCC%11)C%12CCCCC%12

InChI

1S/2C33H49P.2C12H10N.2ClH.2Pd/c1-23(2)27-21-31(24(3)4)33(32(22-27)25(5)6)26-14-13-19-30(20-26)34(28-15-9-7-10-16-28)29-17-11-8-12-18-29;1-23(2)26-21-30(24(3)4)33(31(22-26)25(5)6)29-19-13-14-20-32(29)34(27-15-9-7-10-16-27)28-17-11-8-12-18-28;2*13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;;;;/h13-14,19-25,28-29H,7-12,15-18H2,1-6H3;13-14,19-25,27-28H,7-12,15-18H2,1-6H3;2*1-6,8-9H,13H2;2*1H;;/q;;;;;;2*+1/p-2

InChI key

HMRJFNBZAWHTGN-UHFFFAOYSA-L

相关类别

一般描述

XPhos Pd G2是一种大位阻的单齿二芳基配体。它是 Buchwald第二 代成型催化剂。它经过 快速还原消除反应，形成反应性单膦Pd（0）类化合物。

应用

第二代Buchwald预催化剂

  • 广泛用于Suzuki-Miyaura交叉偶联反应
XPhos Pd G2被用作以下反应的催化剂：
  • 钯催化的有机三氟硼酸钾与氨基磺酸盐的Suzuki-Miyaura偶联反应。
  • 敏感芳基和杂芳基硼酸的Suzuki-Miyaura交叉偶联反应。
  • 通过Suzuki-Miyaura交叉偶联反应，合成钾Boc保护的仲氨基甲基三氟硼酸盐。
对于小规模和高通量应用，该产品也可作为ChemBeads产品提供（927775）

相关产品

产品编号
说明
价格

903728

DavePhos Pd G2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
SHBR9540
SHBQ3483
0000160314
0000159390
0000159390

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Gary A Molander et al.
Organic letters, 15(10), 2534-2537 (2013-05-08)
Sulfamates were studied as the electrophilic partners in the palladium-catalyzed Suzuki-Miyaura cross-coupling reaction with potassium Boc-protected primary and secondary aminomethyltrifluoroborates. A broad range of substrates was successfully coupled to provide the desired products. Complex molecules containing a new carbon-carbon bond
Gary A Molander et al.
Organic letters, 14(17), 4458-4461 (2012-08-31)
Seven potassium Boc-protected secondary aminomethyltrifluoroborates were prepared in a standardized two-step process. The Suzuki-Miyaura cross-coupling reaction was studied with this new class of nucleophiles, and a large variety of aryl and hetaryl chlorides provided the desired products in good to
Gary A Molander et al.
The Journal of organic chemistry, 78(8), 4123-4131 (2013-04-11)
A method has been developed for the Pd-catalyzed synthesis of α-(hetero)aryl esters and amides through a Suzuki-Miyaura cross-coupling reaction. This method avoids the use of strong base, does not necessitate inert or low temperature formation of reagents, and does not

商品

2nd Generation Buchwald Precatalysts

Buchwald precatalysts and ligands are bulky electron-rich dialkylbiaryl phospine-based catalysts and structurally related ligands that improve reactivity in Pd-catalyzed cross - coupling reactions

Heck反应应用和产品

Heck反应是烯烃与芳基或乙烯基卤化物（或三氟甲磺酸酯）之间的钯催化交叉偶联反应，用于生成取代的烯烃。

相关内容

Buchwald and non-Buchwald catalysts and ligands for pharma or industrial chemistry applications

Explore reliable, premium grade catalysis materials for your pharma or industrial project. Specialty chemicals and formulations are available in bulk quantities and volumes from a few grams to multi-metric tons with complete documentation to simplify your leap from development to commercialization.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门