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Merck
CN

72351

Sigma-Aldrich

烟酸苄酯

≥98.0% (GC)

别名:

烟酸苯基甲酯

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About This Item

经验公式(希尔记法):
C13H11NO2
CAS号:
分子量:
213.23
Beilstein:
159169
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

≥98.0% (GC)

表单

liquid

折射率

n20/D 1.570

沸点

177 °C/8 mmHg (lit.)

mp

24 °C (lit.)

官能团

ester
phenyl

SMILES字符串

O=C(OCc1ccccc1)c2cccnc2

InChI

1S/C13H11NO2/c15-13(12-7-4-8-14-9-12)16-10-11-5-2-1-3-6-11/h1-9H,10H2

InChI key

KVYGGMBOZFWZBQ-UHFFFAOYSA-N

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一般描述

Benzyl nicotinate is a benzyl ester. It is a vasodilator agent and is also generally used in cosmetics and drugs.

应用

Benzyl nicotinate can be used for the synthesis of benzylpalladium complexes to be used as catalysts for the substitution of olefins with benzylic groups.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K Neukam et al.
Skin pharmacology and physiology, 24(2), 67-74 (2010-11-20)
Skin sensitivity is a common problem in the Western population correlated with changes of skin properties like skin barrier function, hydration and skin physiology. Skin properties can be modulated by dietary fatty acids (FA), especially poly-unsaturated FA. The present study
Jean-Michel Andanson et al.
Journal of biomedical optics, 14(3), 034011-034011 (2009-07-02)
Infrared (IR) spectroscopy is one of the most chemically specific analytical methods that gives information about composition, structure, and interactions in a material. IR spectroscopy has been successfully applied to study the permeation of xenobiotics through the skin. Combining IR
Ute Jacobi et al.
Journal of biomedical optics, 11(1), 014025-014025 (2006-03-11)
The topical application of drugs, such as nicotinates, affects cutaneous blood flow. Such a biological response, which is dependent on the drug and the individual, can be measured noninvasively using laser Doppler flowmetry. We illustrate the kinetics of vasodilation caused
Efficient transesterification/acylation reactions mediated by N-heterocyclic carbene catalysts.
Grasa GA, et al.
The Journal of Organic Chemistry, 68(7), 2812-2819 (2003)
Francesca Palombo et al.
Journal of biomedical optics, 14(4), 044008-044008 (2009-09-04)
Diffusion of two model drugs-benzyl nicotinate and ibuprofen-and the plasma macromolecule albumin across atherosclerotic rabbit aorta was studied ex vivo by attenuated total reflection-Fourier transform infrared (ATR-FTIR) imaging. Solutions of these molecules were applied to the endothelial surface of histological

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