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Merck
CN

656364

Sigma-Aldrich

(S)-(+)-3-哌啶甲酸

97%

别名:

(S)-(+)-甲酸哌啶

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About This Item

经验公式(希尔记法):
C6H11NO2
CAS号:
分子量:
129.16
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

97%

表单

solid

旋光性

[α]/D 3.0 to 6.5°, c = 1 in H2O

mp

254 °C (dec.)

官能团

carboxylic acid

SMILES字符串

OC(=O)[C@H]1CCCNC1

InChI

1S/C6H11NO2/c8-6(9)5-2-1-3-7-4-5/h5,7H,1-4H2,(H,8,9)/t5-/m0/s1

InChI key

XJLSEXAGTJCILF-YFKPBYRVSA-N

基因信息

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一般描述

(S)-(-)-3-Piperidinecarboxylic acid is an inhibitor of GABA (γ-aminobutyric acid) uptake.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Experimental physiology, 95(7), 774-787 (2010-04-27)
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Zolpidem is a widely prescribed sleep aid with relative selectivity for GABA(A) receptors containing alpha1-3 subunits. We examined the effects of zolpidem on the inhibitory currents mediated by GABA(A) receptors using whole-cell patch-clamp recordings from DMV neurons in transverse brainstem
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Molecules (Basel, Switzerland), 14(9), 3268-3274 (2009-09-29)
As a novel example of improved entry of poorly delivered drugs into the brain by means of nutrient conjugates, L-carnitine was conjugated to nipecotic acid and the capacity to antagonize PTZ-induced convulsions of this novel entity was evaluated.

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