Application
三氟甲磺酰胺可在硫酸中与多聚甲醛发生反应，得到相应的开链和环状缩合产物，或在乙酸乙酯中得到相应的羟甲基化产物。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
"Oxymethylation of trifluoromethanesulfonamide with paraformaldehyde in ethyl acetate"
Meshcheryakov.I.V, et al.
Russ. J. Org. Chem., 44(02), 311-316 (2008)
C J Lynch et al.
The Biochemical journal, 310 ( Pt 1), 197-202 (1995-08-15)
The role of carbonic anhydrase in de novo lipid synthesis was examined by measuring [1-14C]acetate incorporation into total lipids, fatty acids and non-saponifiable lipids in freshly isolated rat hepatocytes. Two carbonic anhydrase inhibitors, trifluoromethylsulphonamide (TFMS) and ethoxozolamide (ETZ) decreased incorporation
Marine Soulié et al.
Physical chemistry chemical physics : PCCP, 18(43), 29999-30008 (2016-11-03)
The arrangement of an ionic fluorophore in the crystalline state was regulated by the presence of various counter-ions and the effect on spectroscopic and self-association properties was studied. To do so, nine salts of berberine (i.e. a fluorescent natural alkaloid)
Hitoshi Nakayama et al.
Chemical & pharmaceutical bulletin, 59(8), 1069-1072 (2011-08-02)
N-[2-(2,4-Difluorophenoxy)trifluoromethyl-3-pyridyl]sulfonamide derivatives 3-6 were prepared by the reaction of 3-pyridylamines and sulfonyl chlorides. Inhibitory activities of these compounds toward secretory phospholipase A₂ (sPLA₂) were examined and N-[2-(2,4-difluorophenoxy)-5-trifluoromethyl-3-pyridyl]-2-naphthalenesulfonamide (5c) was found to be the most potent against sPLA₂ with an IC₅₀
Lina Baranauskienė et al.
BMC biophysics, 5, 12-12 (2012-06-09)
Human carbonic anhydrases (CAs) play crucial role in various physiological processes including carbon dioxide and hydrocarbon transport, acid homeostasis, biosynthetic reactions, and various pathological processes, especially tumor progression. Therefore, CAs are interesting targets for pharmaceutical research. The structure-activity relationships (SAR)
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