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质量水平
方案
96%
表单
powder
mp
171-175 °C (lit.)
官能团
carboxylic acid
ester
SMILES字符串
OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2
InChI
1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1
InChI key
DOUMFZQKYFQNTF-WUTVXBCWSA-N
基因信息
human ... LCK(3932)
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一般描述
迷迭香酸是一种具有抗氧化和抗炎作用的生物活性植物酚类化合物。
应用
迷迭香酸被用作模型化合物，以研究其在动物模型中的生物学效应。多项研究表明其具有以下作用：
- 抑制肾病。
- 抑制硫酸庆大霉素（GS）诱导的肾脏氧化损伤。
- 缓解噪音引起的听力损失。
- 缓解抑郁。
- 缓解创伤后应激障碍（PTSD）样症状。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Rosmarinic acid ameliorates PTSD-like symptoms in a rat model and promotes cell proliferation in the hippocampus.
Nie H, et al.
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 51, 16-22 (2014)
Potential Albumin-Based Antioxidant Nanoformulations for Ocular Protection against Oxidative Stress.
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Amongst various drug administration methods, ophthalmic drug delivery has been a useful way for the treatment of eye-related diseases. However, therapeutic efficacy of ocular therapy for anterior or posterior eye segments through topical administration is considerably challenged by the number
Rosmarinic acid up-regulates the noise-activated Nrf2/HO-1 pathway and protects against noise-induced injury in rat cochlea.
Fetoni A R, et al.
Free Radical Biology & Medicine, 83, 269-281 (2015)
Rosmarinic acid ameliorates diabetic nephropathy in uninephrectomized diabetic rats.
Tavafi M, et al.
Iranian Journal of Basic Medical Sciences, 14(3), 275-275 (2011)
Effect of rosmarinic acid on inhibition of gentamicin induced nephrotoxicity in rats.
Tavafi M and Ahmadvand H
Tissue & cell, 43(6), 392-397 (2011)
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