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Merck
CN

535311

聚 N -异丙基丙烯酰胺

Mn ~40,000

别名:

NIPAM 聚合物, PNIPAM, 聚NIPAM, 聚丙烯酰胺

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关于此项目

线性分子式:
CH3(C6H11NO)nCH3
化学文摘社编号:
25189-55-3
MDL编号:
MFCD00284282
UNSPSC代码:
12162002
PubChem化学物质编号:
24877546
NACRES:
NA.23

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分子量

Mn 20,000-60,000
Mn ~40,000

质量水平

100

mp

96 °C

SMILES字符串

CC(C)NC(=O)C=C

InChI

1S/C6H11NO/c1-3-5-7-6(8)4-2/h4H,2-3,5H2,1H3,(H,7,8)

InChI key

WDFKEEALECCKTJ-UHFFFAOYSA-N

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应用

细胞膜片组织工程用PNIPAM类智能表面
热敏聚合物可用于形成水凝胶。当温度升至ca. 32 °C时，聚合物水溶液发生相变，即从可溶状态转变为不溶状态。

外形

热敏聚合物，水凝胶

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000491042
0000491042
MKCX8171
MKCV7874
MKCR8778

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Yan Xia et al.
Chemical communications (Cambridge, England), 49(25), 2566-2568 (2013-02-21)
Site-specific protein conjugates with RAFT polymers were synthesized using expressed protein ligation. Stable micelles were formed from both linear block copolymer and Y-shaped conjugates.
Kornelia Gawlitza et al.
Physical chemistry chemical physics : PCCP, 14(27), 9594-9600 (2012-06-12)
The aim of the present work is the use of a water soluble enzyme in an organic solvent, still with a pronounced catalytic activity. Therefore, lipase B from Candida antarctica (CalB) is immobilized within micron-sized thermosensitive p-NIPAM hydrogel particles using
Jinseok Byun et al.
Chemical communications (Cambridge, England), 48(74), 9278-9280 (2012-08-09)
We report a novel approach for the fabrication of a photo-responsive surface with fast and reversibly switchable wettability between hydrophobicity and hydrophilicity induced by a photothermal effect.
Guiying Li et al.
International journal of biological macromolecules, 50(4), 899-904 (2012-06-09)
Thermo-sensitive poly(N-isopropyl acrylamide-co-vinyl pyrrolidone)/chitosan [P(NIPAM-co-NVP)/CS] semi-IPN hydrogels with improved loading capacity and sustained release for anionic drugs NAP were prepared by free-radical polymerization. The LCST of hydrogels was adjusted to the vicinity of body temperature by introducing hydrophilic NVP. The
Albert J de Graaf et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(3), 582-590 (2012-09-14)
In this paper it is shown that when a thermosensitive hydrogel based on poly(N-isopropylacrylamide)-poly(ethylene glycol)-poly(N-isopropylacrylamide) (pNIPAm-PEG-pNIPAm) was transferred into water, flower-like micelles were continuously released as long as the medium was regularly refreshed. On the other hand, if the medium
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