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Merck
CN

535311

Sigma-Aldrich

N -异丙基丙烯酰胺

Mn ~40,000

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别名:
NIPAM 聚合物, PNIPAM, 聚NIPAM, 聚丙烯酰胺
线性分子式:
CH3(C6H11NO)nCH3
CAS号:
MDL编号:
UNSPSC代码:
12162002
PubChem化学物质编号:
NACRES:
NA.23

分子量

Mn 20,000-60,000
Mn ~40,000

质量水平

mp

96 °C

SMILES字符串

CC(C)NC(=O)C=C

InChI

1S/C6H11NO/c1-3-5-7-6(8)4-2/h4H,2-3,5H2,1H3,(H,7,8)

InChI key

WDFKEEALECCKTJ-UHFFFAOYSA-N

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相关类别

应用

热敏聚合物可用于形成水凝胶。当温度升至ca. 32 °C时,聚合物水溶液发生相变,即从可溶状态转变为不溶状态。

外形

热敏聚合物,水凝胶

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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Kornelia Gawlitza et al.
Physical chemistry chemical physics : PCCP, 14(27), 9594-9600 (2012-06-12)
The aim of the present work is the use of a water soluble enzyme in an organic solvent, still with a pronounced catalytic activity. Therefore, lipase B from Candida antarctica (CalB) is immobilized within micron-sized thermosensitive p-NIPAM hydrogel particles using
Yan Xia et al.
Chemical communications (Cambridge, England), 49(25), 2566-2568 (2013-02-21)
Site-specific protein conjugates with RAFT polymers were synthesized using expressed protein ligation. Stable micelles were formed from both linear block copolymer and Y-shaped conjugates.
Jinseok Byun et al.
Chemical communications (Cambridge, England), 48(74), 9278-9280 (2012-08-09)
We report a novel approach for the fabrication of a photo-responsive surface with fast and reversibly switchable wettability between hydrophobicity and hydrophilicity induced by a photothermal effect.
Albert J de Graaf et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(3), 582-590 (2012-09-14)
In this paper it is shown that when a thermosensitive hydrogel based on poly(N-isopropylacrylamide)-poly(ethylene glycol)-poly(N-isopropylacrylamide) (pNIPAm-PEG-pNIPAm) was transferred into water, flower-like micelles were continuously released as long as the medium was regularly refreshed. On the other hand, if the medium
Guiying Li et al.
International journal of biological macromolecules, 50(4), 899-904 (2012-06-09)
Thermo-sensitive poly(N-isopropyl acrylamide-co-vinyl pyrrolidone)/chitosan [P(NIPAM-co-NVP)/CS] semi-IPN hydrogels with improved loading capacity and sustained release for anionic drugs NAP were prepared by free-radical polymerization. The LCST of hydrogels was adjusted to the vicinity of body temperature by introducing hydrophilic NVP. The

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The present publication focuses on synthesis and characterization of nanothick, chemically grafted polymer films (polymer brushes) on various inorganic and polymeric substrates.

Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.

组织工程已成为治疗受损或患病的器官和组织(例如血管和尿囊)的关键治疗工具。

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

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