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Merck
CN

535311

聚 N -异丙基丙烯酰胺

Mn ~40,000

别名:

NIPAM 聚合物, PNIPAM, 聚NIPAM, 聚丙烯酰胺

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关于此项目

线性分子式:
CH3(C6H11NO)nCH3
化学文摘社编号:
25189-55-3
NACRES:
NA.23
PubChem Substance ID:
24877546
UNSPSC Code:
12162002
MDL number:
MFCD00284282

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InChI

1S/C6H11NO/c1-3-5-7-6(8)4-2/h4H,2-3,5H2,1H3,(H,7,8)

SMILES string

CC(C)NC(=O)C=C

InChI key

WDFKEEALECCKTJ-UHFFFAOYSA-N

mol wt

Mn 20,000-60,000, Mn ~40,000

mp

96 °C

Quality Level

100

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相关类别

Application

细胞膜片组织工程用PNIPAM类智能表面
热敏聚合物可用于形成水凝胶。当温度升至ca. 32 °C时，聚合物水溶液发生相变，即从可溶状态转变为不溶状态。

Physical form

热敏聚合物，水凝胶

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000491042
0000491042
MKCX8171
MKCV7874
MKCR8778

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Soichi Takagi et al.
Cell transplantation, 21(2-3), 411-420 (2012-07-17)
The de novo engineering of a uniform hepatocyte sheet in vitro is considered as a novel approach for liver-directed therapeutics. Hepatocytes can be cultured on a temperature-responsive culture dishes coated with poly(N-isopropylacrylamide) (PIPAAm). Following multiple days of culturing, the
Avraham Halperin et al.
Langmuir : the ACS journal of surfaces and colloids, 28(48), 16623-16637 (2012-11-06)
Thermoresponsive tissue culture substrates based on PNIPAM brushes are used to harvest confluent cell sheets for tissue engineering. The prospect of clinical use imposes the utilization of culture medium free of bovine serum, thus suggesting conjugation with adhesion peptides containing
Umut Atakan Gurkan et al.
Advanced healthcare materials, 1(5), 661-668 (2012-11-28)
Stimuli responsive, smart interface materials are integrated with microfluidic technologies creating new functions for a broad range of biological and clinical applications by controlling the material and cell interactions. Local capture and on-demand local release of cells are demonstrated with
Tatiya Trongsatitkul et al.
Colloids and surfaces. B, Biointerfaces, 103, 244-252 (2012-12-04)
The effect of PEGylation on the thermal response and protein adsorption resistance of crosslinked PNIPAm microgels was investigated. It was found that the presence of PEG, its molecular weight (M(n) 300 and 1100 g/mol) and its concentration (10, 20, and
Hydrophobic interaction-mediated capture and release of cancer cells on thermoresponsive nanostructured surfaces.
Hongliang Liu et al.
Advanced materials (Deerfield Beach, Fla.), 25(6), 922-927 (2012-11-20)
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