蒸汽密度
9.6 (vs air)
质量水平
蒸汽压
1 mmHg ( 147 °C)
检测方案
99%
形式
liquid
自燃温度
756 °F
expl. lim.
0.47 %, 236 °F
杂质
≤0.005% Acidity (as Phthalic acid)
≤0.15% water
颜色
APHA: ≤20
折射率
n20/D 1.492 (lit.)
pH值（酸碱度）
7 (20 °C, 10 mg/L)
bp
340 °C (lit.)
mp
−35 °C (lit.)
密度
1.043 g/mL at 25 °C (lit.)
SMILES字符串
CCCCOC(=O)c1ccccc1C(=O)OCCCC
InChI
1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3
InChI key
DOIRQSBPFJWKBE-UHFFFAOYSA-N
基因信息
mouse ... Esr1(13982)
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一般描述
邻苯二甲酸二丁酯（DBP）最常用作各种家用产品中的增塑剂。在使用或处理这些产品时，它可以浸出和蒸发到环境中。因此，针对其毒性和细胞凋亡效应的研究正在进行。研究还表明，接触高剂量的DBP可能会干扰黄体酮和雌二醇的产生。
应用
增塑剂
警示用语：
Danger
危险声明
危险分类
Aquatic Acute 1 - Aquatic Chronic 2 - Repr. 1B
WGK
WGK 3
闪点(°F)
open cup
闪点(°C)
open cup
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
农药列管产品
Dibutyl phthalate (DBP)-induced apoptosis and neurotoxicity are mediated via the aryl hydrocarbon receptor (AhR) but not by estrogen receptor alpha (ER?), estrogen receptor beta (ER?), or peroxisome proliferator-activated receptor gamma (PPAR?) in mouse cortical neurons.
Wojtowicz A
Neurotoxicity Research, 31(1), 77-89 (2017)
Dibutyl phthalate impairs steroidogenesis and a subset of LH-dependent genes in cultured human mural granulosa cell in vitro.
Adir M
Reproductive Toxicology, 69, 13-18 (2017)
Linda V Sinclair et al.
Immunometabolism, 2(4), e200029-e200029 (2020-09-04)
Assays to monitor the metabolic state or nutrient uptake capacity of immune cells at a single cell level are increasingly in demand. One assay, used by many immunologists, employs 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG), a fluorescent analogue of 2-deoxyglucose (2DG), as a substrate
Damien Hunter et al.
International journal of molecular sciences, 22(8) (2021-05-01)
Xenobiotic exposure during pregnancy and lactation has been linked to perinatal changes in male reproductive outcomes and other endocrine parameters. This pilot study wished to assess whether brief maternal exposure of rats to xenobiotics dibutyl phthalate (DBP) or diethylstilbestrol (DES)
Alin C Dirtu et al.
Environment international, 59, 344-353 (2013-07-31)
Human exposure to chemicals commonly encountered in our environment, like phthalates, is routinely assessed through urinary measurement of their metabolites. A particular attention is given to the specific population groups, such as obese, for which the dietary intake of environmental
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