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质量水平
方案
98%
表单
solid
旋光性
[α]27/D +65°, c = 1.2 in ethanol
mp
162 °C (dec.) (lit.)
官能团
carboxylic acid
SMILES字符串
Cc1c(C)c2O[C@](C)(CCc2c(C)c1O)C(O)=O
InChI
1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)/t14-/m1/s1
InChI key
GLEVLJDDWXEYCO-CQSZACIVSA-N
一般描述
( R )-(+)-6-羟基-2，5，7，8-四甲基色-2-羧酸，为维生素 E 类似物，是一种蘑菇酪氨酸酶抑制剂。
应用
当设计基于γ-氨基丁酸（GABA）的抗应激剂时。（R） - （+） - 6-羟基-2,5,7,8-四甲基色满-2-羧酸可用于结合抗氧化性能。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Shyamal Subramanyam et al.
Methods in enzymology, 600, 201-232 (2018-02-21)
Human RAD51 promotes accurate DNA repair by homologous recombination and is involved in protection and repair of damaged DNA replication forks. The active species of RAD51 and related recombinases in all organisms is a nucleoprotein filament assembled on single-stranded DNA
Inhibitory effects of (S)-and (R)-6-hydroxy-2, 5, 7, 8-tetramethylchroman-2-carboxylic acids on tyrosinase activity.
Yu L.
Journal of Agricultural and Food Chemistry, 51(8), 2344-2347 (2003)
Novel compounds designed as antistress agents.
Tsiakitzis, KC, et al.
Journal of Medicinal Chemistry, 52(22), 7315-7318 (2009)
Helena Moreira et al.
Acta poloniae pharmaceutica, 74(2), 688-698 (2018-04-07)
Polyphenol rich extracts obtained from cistus herb (Cistus incanus L.) and pomegranate peel (Punica granatum L.) exhibited significant antioxidant activity in V79 cell culture (Chinese hamster lung fibroblasts) -cistus extract reduced intracellular content of reactive oxygen species (ROS) by 30-40%
Aleksandra Slezak et al.
Acta poloniae pharmaceutica, 74(2), 670-678 (2018-04-07)
Polyphenol rich extracts obtained from cistus herb (Cistus incanus L.) and pomegranate peels (Punica granatunm L.) added at high concentrations (25-100 pg/mL) to V79 (Chinese hamster lung fibroblast) cell cultures, markedly increased intracellular level of ROS (reactive oxygen species). Also
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