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Merck
CN

284599

Sigma-Aldrich

毒藜碱

≥97%

别名:

2-(3-吡啶基)哌啶, 新烟碱

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About This Item

经验公式(希尔记法):
C10H14N2
CAS号:
分子量:
162.23
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

≥97%

形式

liquid

折射率

n20/D 1.544 (lit.)

bp

96 °C/12 mmHg (lit.)

密度

1.046 g/mL at 25 °C (lit.)

应用

agriculture
environmental

SMILES字符串

C1CCC(NC1)c2cccnc2

InChI

1S/C10H14N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h3-4,6,8,10,12H,1-2,5,7H2

InChI key

MTXSIJUGVMTTMU-UHFFFAOYSA-N

基因信息

一般描述

Anabasine inhibited androstenedione conversion to estrogen in a dose-dependent manner.

应用

Anabasine, a tobacco alkaloid, was used as a biomarker of active tobacco use.

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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R L Barbieri et al.
The Journal of clinical investigation, 77(6), 1727-1733 (1986-06-01)
Epidemiologic studies suggest that women who smoke have lower endogenous estrogen than nonsmokers. To explore the possible link between cigarette smoking and decreased endogenous estrogens, we have examined the effects of constituents of tobacco on estrogen production in human choriocarcinoma
Brenda B Suh-Lailam et al.
Journal of analytical toxicology, 38(7), 416-420 (2014-06-19)
Laboratory detection of nicotine exposure is important for establishing eligibility for organ transplant and elective surgery. Nicotine testing is also used to verify compliance with nicotine replacement therapies (NRT), smoking cessation programs and for life insurance purposes. Nicotine metabolites, such
J L Castorena et al.
Journal of toxicology. Clinical toxicology, 25(5), 429-435 (1987-01-01)
A young adult male was found dead in a field. No cause of death was apparent at autopsy, and the only positive toxicological finding was the presence of a nicotine-like alkaloid isolated from the liver. Anabasine, the major, highly toxic
N Mizrachi et al.
Journal of forensic sciences, 45(3), 736-741 (2000-06-16)
Death of a worker occurred after ingestion of unknown amounts of Nicotiana glauca G leaves. The leaves were cooked after having been mistakenly considered to be spices of a type which grow in Thailand. After ingestion, two Thai workers collapsed
Xu Xu et al.
Clinical chemistry, 50(12), 2323-2330 (2004-10-09)
Determination of nicotine metabolism/pharmacokinetics provides a useful tool for estimating uptake of nicotine and tobacco-related toxicants, for understanding the pharmacologic effects of nicotine and nicotine addiction, and for optimizing nicotine dependency treatment. We developed a sensitive method for analysis of

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