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描述
chromophore for enzyme substrates
质量水平
检测方案
99%
形式
solid
mp
223-226 °C (lit.)
λmax
354 nm in ethanol
储存温度
2-8°C
SMILES字符串
CC1=CC(=O)Oc2cc(N)ccc12
InChI
1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3
InChI key
GLNDAGDHSLMOKX-UHFFFAOYSA-N
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一般描述
7-氨基-4-甲基香豆素(香豆素120)是一种氨基香豆素激光染料,可发出370-760 nm范围内的激光。它含有三个C-H···O和N-H····O分子间氢键结构。
应用
香豆素120可作为荧光标记试剂,用于痕量酶的测定。由于它可影响细胞形态,因而可用作抗结核分枝杆菌MDR分离株的抗菌剂。香豆素120也可用作电子供体(氨基),以转移荧光传感器中的电荷,以检测水性介质中的汞离子。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
7-Amino-4-methylcoumarin.
Acta Crystallographica Section C, Crystal Structure Communications, 50(12), 1954-1956 (1994)
A ?turn-on? coumarin-based fluorescent sensor with high selectivity for mercury ions in aqueous media.
Chemical Communications (Cambridge, England), 46(19), 3292-3294 (2010)
Fluorescence quenching of 7-amino-4-methylcoumarin by different TEMPO derivatives.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 136(12), 1875-1880 (2015)
Chemphyschem : a European journal of chemical physics and physical chemistry, 11(16), 3534-3540 (2010-10-26)
Herein the reactivity of the enzyme α-chymotrypsin in the confinement of polystyrene-block-poly(acrylic acid) (PS-b-PAA) vesicles was investigated. Enzyme and substrate molecules were encapsulated in PS-b-PAA vesicles with internal diameters ranging from 26 nm to 165 nm during the formation of
Journal of the American Chemical Society, 130(38), 12564-12565 (2008-09-03)
We described here a coumarin-based dual-excitation ratiometric probe for cadmium, CadMQ. This fluorescence sensor has high quantum yields of 0.59 and 0.70 in the metal-free and Cd2+-bound forms, respectively, and has a dissociation constant of 0.16 nM for Cd2+. CadMQ
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