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Merck
CN

257370

Sigma-Aldrich

7-氨基-4-甲基香豆素

99%

别名:

香豆素 120

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About This Item

经验公式(希尔记法):
C10H9NO2
CAS号:
分子量:
175.18
Beilstein:
142231
EC 号:
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.23

描述

chromophore for enzyme substrates

质量水平

方案

99%

表单

solid

mp

223-226 °C (lit.)

λmax

354 nm in ethanol

储存温度

2-8°C

SMILES字符串

CC1=CC(=O)Oc2cc(N)ccc12

InChI

1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3

InChI key

GLNDAGDHSLMOKX-UHFFFAOYSA-N

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一般描述

7-氨基-4-甲基香豆素(香豆素120)是一种氨基香豆素激光染料,可发出370-760 nm范围内的激光。它含有三个C-H···O和N-H····O分子间氢键结构。

应用

香豆素120可作为荧光标记试剂,用于痕量酶的测定。由于它可影响细胞形态,因而可用作抗结核分枝杆菌MDR分离株的抗菌剂。香豆素120也可用作电子供体(氨基),以转移荧光传感器中的电荷,以检测水性介质中的汞离子。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Fluorescence quenching of 7-amino-4-methylcoumarin by different TEMPO derivatives.
Zamojc K, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 136(12), 1875-1880 (2015)
7-Amino-4-methylcoumarin.
Jasinski J and Woudenberg R
Acta Crystallographica Section C, Crystal Structure Communications, 50(12), 1954-1956 (1994)
A ?turn-on? coumarin-based fluorescent sensor with high selectivity for mercury ions in aqueous media.
Voutsadaki S, et al.
Chemical Communications (Cambridge, England), 46(19), 3292-3294 (2010)
Aldrichimica Acta, 15, 42-42 (1982)
Qi Chen et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 11(16), 3534-3540 (2010-10-26)
Herein the reactivity of the enzyme α-chymotrypsin in the confinement of polystyrene-block-poly(acrylic acid) (PS-b-PAA) vesicles was investigated. Enzyme and substrate molecules were encapsulated in PS-b-PAA vesicles with internal diameters ranging from 26 nm to 165 nm during the formation of

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