257370
7-氨基-4-甲基香豆素
99%
别名:
香豆素 120
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关于此项目
经验公式（希尔记法）:
C10H9NO2
化学文摘社编号:
分子量:
175.18
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
247-454-8
Beilstein/REAXYS Number:
142231
MDL number:
产品名称
7-氨基-4-甲基香豆素, 99%
InChI key
GLNDAGDHSLMOKX-UHFFFAOYSA-N
InChI
1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3
SMILES string
CC1=CC(=O)Oc2cc(N)ccc12
description
chromophore for enzyme substrates
assay
99%
form
solid
mp
223-226 °C (lit.)
λmax
354 nm in ethanol
storage temp.
2-8°C
Quality Level
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Application
香豆素120可作为荧光标记试剂，用于痕量酶的测定。由于它可影响细胞形态，因而可用作抗结核分枝杆菌MDR分离株的抗菌剂。香豆素120也可用作电子供体（氨基），以转移荧光传感器中的电荷，以检测水性介质中的汞离子。
General description
7-氨基-4-甲基香豆素（香豆素120）是一种氨基香豆素激光染料，可发出370-760 nm范围内的激光。它含有三个C-H···O和N-H····O分子间氢键结构。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Fluorescence quenching of 7-amino-4-methylcoumarin by different TEMPO derivatives.
Zamojc K, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 136(12), 1875-1880 (2015)
7-Amino-4-methylcoumarin.
Jasinski J and Woudenberg R
Acta Crystallographica Section C, Crystal Structure Communications, 50(12), 1954-1956 (1994)
A ?turn-on? coumarin-based fluorescent sensor with high selectivity for mercury ions in aqueous media.
Voutsadaki S, et al.
Chemical Communications (Cambridge, England), 46(19), 3292-3294 (2010)
Aldrichimica Acta, 15, 42-42 (1982)
Sander S van Berkel et al.
ChemMedChem, 7(4), 606-617 (2012-02-02)
The synthesis of a series of peptides containing C-terminal 7-amino-4-methylcoumarin (AMC) for use in the thrombin generation test (TGT) is described. The lead structure in this project was H-Gly-Gly-Arg-AMC, of which the water solubility and kinetic parameters (K(M) and k(cat))
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