质量水平
检测方案
98%
mp
>300 °C (lit.)
SMILES字符串
CN1C(=O)NC(=O)c2[nH]cnc12
InChI
1S/C6H6N4O2/c1-10-4-3(7-2-8-4)5(11)9-6(10)12/h2H,1H3,(H,7,8)(H,9,11,12)
InChI key
GMSNIKWWOQHZGF-UHFFFAOYSA-N
基因信息
rat ... Adora1(29290) , Adora2a(25369)
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一般描述
通过灵敏的LC-MS/MS方法定量测定大鼠血浆中茶碱的代谢产物3-甲基黄嘌呤。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
M C Rogge et al.
Clinical pharmacology and therapeutics, 46(4), 420-428 (1989-10-01)
The pharmacokinetics of theophylline and its three major metabolites, 3-methylxanthine, 1-methylurate, and 1,3-dimethylurate, were studied during intermittent administration of enoxacin. The addition of enoxacin (400 mg, twice daily) to a theophylline dosing regimen (150 mg, twice daily) resulted in an
Hira Sajjad Talpur et al.
Reproductive biology, 17(4), 380-388 (2017-11-04)
Melatonin receptor 1 (MT1) performs a critical role in the regulation of the animal reproductive system, particularly in follicular growth, and has a considerable effect on reproductive performance. However, the role that MT1 plays in regulating hormones associated with reproduction
Binxing Zhou et al.
Journal of food science, 85(2), 477-485 (2020-01-07)
Natural microorganisms involved in solid-state fermentation (SSF) of Pu-erh tea have a significant impact on its chemical components. Aspergillus sydowii is a fungus with a high caffeine-degrading capacity. In this work, A. sydowii was inoculated into sun-dried green tea leaves
Shawn K Desai et al.
Journal of the American Chemical Society, 126(41), 13247-13254 (2004-10-14)
Genetic selection provides the most powerful method to assay large libraries of biomolecules for function. However, harnessing the power of genetic selection for the detection of specific, nonendogenous small-molecule targets in vivo remains a significant challenge. The ability to genetically
Sandrine Derkenne et al.
Pharmacogenetics and genomics, 15(7), 503-511 (2005-06-23)
Pharmacokinetics of theophylline was investigated in Cyp1(+/+) wild-type mice, Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, and humanized hCYP1A1_1A2 mice lacking either the mouse Cyp1a1 or Cyp1a2 gene. Animals received a single dose of theophylline (8 mg/kg i.p.), either alone or pretreated
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