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Merck
CN

219991

Sigma-Aldrich

4-咪唑乙酸 盐酸盐

98%

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别名:
(4-咪唑基)乙酸 盐酸盐, I4AA
经验公式(希尔记法):
C5H6N2O2 · HCl
CAS号:
分子量:
162.57
Beilstein:
3701591
EC 号:
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

98%

形式

solid

mp

218-222 °C (lit.)

溶解性

water: soluble 100 mg/mL, clear, faintly yellow

SMILES字符串

Cl.OC(=O)Cc1c[nH]cn1

InChI

1S/C5H6N2O2.ClH/c8-5(9)1-4-2-6-3-7-4;/h2-3H,1H2,(H,6,7)(H,8,9);1H

InChI key

MWHLCFYPFGFBQO-UHFFFAOYSA-N

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应用

在以下合成中使用了 4-咪唑乙酸盐酸盐:
  • 咪唑基-聚乙烯亚胺改性纳米颗粒
  • 潜在金属离子螯合剂吡啶基和咪唑基功能化碳蛋白

生化/生理作用

GABAC 受体上的竞争性拮抗剂。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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A Pernille Tofteng et al.
Organic & biomolecular chemistry, 5(14), 2225-2233 (2007-07-05)
De novo design and total chemical synthesis of proteins provides a powerful approach for biological and biophysical studies with the ability to prepare artificial proteins with tailored properties, potentially of importance for biophysical studies, material science, nanobioscience, and as molecular
Archana Swami et al.
International journal of pharmaceutics, 335(1-2), 180-192 (2006-12-16)
The derivatives of polyethylenimine (PEI 25 and 750kDa) were synthesized by partially substituting their amino groups with imidazolyl moieties. The series of imidazolyl-PEIs thus obtained were cross-linked with polyethylene glycol (PEG) to get imidazolyl-PEI-PEG nanoparticles (IPP). The component of hydrophobicity
A Kammeyer et al.
Biochimica et biophysica acta, 1526(3), 277-285 (2001-06-19)
cis-Urocanic acid (cis-UCA), formed from trans-urocanic acid (trans-UCA) by photoisomerization, has been shown to mimic suppressive effects of UV on the immune system. It is our hypothesis that UCA oxidation products in the skin play a role in the process
Yuya Oaki et al.
Nanoscale, 2(11), 2362-2365 (2010-09-14)
The organization of an imidazolium salt in the interlayer space of a layered inorganic compound leads to the formation of nanosegregated composites.
Zihao Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(37), 13793-13798 (2008-09-10)
Protein GlcNAcylation serves as a nutrient/stress sensor to modulate the functions of many nuclear and cytoplasmic proteins. O-GlcNAc cycles on serine or threonine residues like phosphorylation, is nearly as abundant, and functions, at least partially, via its interplay with phosphorylation.

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