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经验公式(希尔记法):
C10H9NO
化学文摘社编号:
分子量:
159.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
226-077-2
Beilstein/REAXYS Number:
115244
MDL number:
产品名称
6-甲氧基喹啉, 98%
InChI key
HFDLDPJYCIEXJP-UHFFFAOYSA-N
InChI
1S/C10H9NO/c1-12-9-4-5-10-8(7-9)3-2-6-11-10/h2-7H,1H3
SMILES string
COc1ccc2ncccc2c1
assay
98%
refractive index
n20/D 1.625 (lit.)
bp
140-146 °C/15 mmHg (lit.)
mp
18-20 °C (lit.)
density
1.15 g/mL at 20 °C (lit.)
Quality Level
Gene Information
human ... CYP2D6(1565)
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Application
6-甲氧基喹啉用作前体,用于合成:
- 荧光锌和氯传感器。
- 5-氨基-2-芳酰基喹啉是有效的微管蛋白聚合抑制剂。
- 3-氟-6-甲氧基喹啉衍生物作为细菌 DNA 旋转酶和拓扑异构酶的抑制剂。
- 钴基三元金属-有机络合物单?离子磁铁。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
>230.0 °F
flash_point_c
> 110 °C
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Richard G Painter et al.
Analytical chemistry, 78(9), 3133-3137 (2006-04-29)
Human neutrophils synthesize hypochlorous acid, a nonradical oxidant, as one of the antimicrobial agents to kill phagocytosed pathogens within phagolysosomes. The production of HOCl is catalyzed by myeloperoxidase using chloride anions (Cl-). Even though various approaches have been documented to
Single-Ion Magnets Based on Mononuclear Cobalt (II) Complexes with Sulfadiazine.
Villa-Perez C, et al.
European Journal of Inorganic Chemistry, 2016(29), 4835-4841 (2016)
Novel 3-fluoro-6-methoxyquinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV.
Mitton-Fry MJ, et al.
Bioorganic & Medicinal Chemistry Letters, 27(15), 3353-3358 (2017)
Roland J Reischl et al.
Journal of chromatography. A, 1269, 262-269 (2012-08-28)
The determination of trace amounts of d-amino acids (d-AAs) even in tissue samples of higher developed animals, mammals and humans has opened a wide field of biological questions to be investigated. d-Ala, d-Asp and d-Ser have already been identified to
Methoxy-substituted TQEN family of fluorescent zinc sensors.
Mikata Y, et al.
Inorganic Chemistry, 45(23), 9262-9268 (2006)
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