119792
罗汉松酸
98%
别名:
(+)-Podocarpic acid, (1S)-1,2,3,4,4a,9,10,10a-Octahydro-6-hydroxy-1,4a-dimethyl-1-phenanthrenecarboxylic acid, (1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-6-hydroxy-1,4a-dimethyl-1-phenanthrenecarboxylic acid, Podocarpic acid (resin acid)
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所有图片(2)
About This Item
经验公式（希尔记法）:
C17H22O3
CAS号:
分子量:
274.35
EC 号:
MDL编号:
UNSPSC代码:
12352002
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
方案
98%
表单
solid
旋光性
[α]20/D +133°, c = 4 in ethanol
mp
193-196 °C (lit.)
官能团
carboxylic acid
SMILES字符串
[H][C@@]12CCc3ccc(O)cc3[C@@]1(C)CCC[C@]2(C)C(O)=O
InChI
1S/C17H22O3/c1-16-8-3-9-17(2,15(19)20)14(16)7-5-11-4-6-12(18)10-13(11)16/h4,6,10,14,18H,3,5,7-9H2,1-2H3,(H,19,20)/t14-,16-,17+/m1/s1
InChI key
VJILEYKNALCDDV-OIISXLGYSA-N
基因信息
human ... TNF(7124)
应用
- (+)-Podocarpic acid as chiral template in the synthesis of aphidicolane, stemodane and stemarane diterpenoids: This article reviews the use of (+)-podocarpic acid in the synthesis of various diterpenoids, showcasing its utility in complex organic syntheses (La Bella et al., 2016).
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Weiguo Liu et al.
Bioorganic & medicinal chemistry letters, 15(20), 4574-4578 (2005-08-30)
A series of podocarpic acid amides were identified as potent agonists for Liver X receptor alpha and beta subtypes, which are members of a nuclear hormone receptor superfamily that are involved in the regulation of a variety of metabolic pathways
K A Staschke et al.
Virology, 248(2), 264-274 (1998-08-29)
Entry of influenza virus into the host cell is dependent on the fusion of the viral envelope with the endosomal membrane and is mediated by a low-pH-induced change of the viral hemagglutinin (HA) to a conformation that is fusogenic. A
Podocarpic acid as a source of an oestrogenic hormone.
C W BRANDT et al.
Nature, 161(4101), 892-892 (1948-06-05)
A E Fidler et al.
Reproduction, fertility, and development, 12(3-4), 191-199 (2001-04-17)
In recent years the possibility of environmental oestrogens affecting the reproduction of vertebrates has become an issue of both public and scientific interest. Although the significance of such chemicals remains controversial there is clear evidence that, in some contexts, environmental
A Johansson et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 103(6), 419-427 (1995-06-01)
Zinc and oleoresins are the main components of several wound dressings, and are also frequently used in root canal treatment. The in vitro antibacterial effects of zinc, six highly purified resin acids and two commercial oleoresins alone or combined in
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