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Merck
CN

E4378

Sigma-Aldrich

乙二醇-双(2-氨基乙醚)-N,N,N′,N′-四乙酸

≥97.0%

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别名:
Chel-DE, EGTA, 乙二醇醚二胺四乙酸, 乙烯-双(氧乙烯硝基)四乙酸, 依他酸
线性分子式:
[-CH2OCH2CH2N(CH2CO2H)2]2
CAS号:
分子量:
380.35
Beilstein:
1717370
EC 号:
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.77

生物来源

synthetic (organic)

质量水平

检测方案

≥97.0%

形式

powder

反应适用性

reagent type: chelator

缺失

≤1.0% loss on drying

mp

241 °C (dec.) (lit.)

溶解性

1 M NaOH: 1.1 g/10 mL, clear, colorless

储存温度

room temp

SMILES字符串

OC(=O)CN(CCOCCOCCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)

InChI key

DEFVIWRASFVYLL-UHFFFAOYSA-N

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应用

乙二醇双(2-氨基乙醚)四乙酸(EGTA)可用于:
  • 作为大鼠主动脉弓缩窄术(TAC)用低温心脏停跳液的组分
  • 作为冰冷裂解缓冲液组分,用于蛋白提取和全细胞提取
  • 作为HEK293F细胞线粒体提取用缓冲液A、B和C的组分

一种螯合剂,可在镁存在的情况下对钙进行测定。

生化/生理作用

乙二醇双(2-氨基乙醚)四乙酸(EGTA)A是一种螯合剂,可在镁存在的情况下对钙进行测定。

物理属性

在水中的溶解性随 pH 值增加而增加

WGK

WGK 2

个人防护装备

Eyeshields, Gloves, type N95 (US)


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