PDGFB
platelet-derived growth factor beta polypeptide
别名:
PDGF-2, PDGF2, SIS, SSV, c-sis
物种:
Human PDGFB (5155), Mouse Pdgfb (18591), Rat Pdgfb (24628), naked mole-rat Pdgfb (101698830), dog PDGFB (442986), sheep PDGFB (443545), domestic guinea pig Pdgfb (100731469), cow PDGFB (540106), chicken PDGFB (374128), Zebrafish pdgfb (565324)
UniProtKB ID:
基因ID:
- Human(5155) Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013]
- Mouse(18591) platelet derived growth factor, B polypeptide
- Rat(24628) platelet-derived growth factor beta polypeptide
- naked mole-rat(101698830) platelet-derived growth factor beta polypeptide
- dog(442986) platelet-derived growth factor beta polypeptide
- sheep(443545) platelet-derived growth factor beta polypeptide
- domestic guinea pig(100731469) platelet-derived growth factor beta polypeptide
- cow(540106) platelet-derived growth factor beta polypeptide
- chicken(374128) platelet-derived growth factor beta polypeptide
- Zebrafish(565324) platelet derived growth factor, B polypeptide
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ELISA
Antibodies
货号
说明
物种反应性
应用
Anti-PDGFB antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
Anti-Platelet-Derived Growth Factor-BB antibody produced in goat, affinity isolated antibody, lyophilized powder,
物种反应性
human
应用
neutralization
western blot
western blot
抗-PDGF-BB抗体, from rabbit, purified by affinity chromatography,
物种反应性
human
应用
ELISA
neutralization
western blot
neutralization
western blot
Anti-PDGFB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-PDGFB antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, human, mouse, rat, sheep
应用
immunohistochemistry
western blot
western blot
Proteins
货号
说明
物种
PDGF-BB，重组，人, The Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle & connective tissue.,
物种
human
esiRNA
货号
说明
物种