MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
别名:
MAPKKK1, MEKK, MEKK 1, MEKK1, SRXY6
物种:
Human MAP3K1 (4214), Mouse Map3k1 (26401), Rat Map3k1 (116667), dog MAP3K1 (478061), Zebrafish map3k1 (100334486), domestic guinea pig Map3k1 (100723456), chicken MAP3K1 (427144), sheep MAP3K1 (101112260), Horse MAP3K1 (100061688), domestic cat MAP3K1 (101090328) ...展开
UniProtKB ID:
基因ID:
- Human(4214) Summary: The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012]
- Mouse(26401) mitogen-activated protein kinase kinase kinase 1
- Rat(116667) mitogen activated protein kinase kinase kinase 1
- dog(478061) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- Zebrafish(100334486) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- domestic guinea pig(100723456) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- chicken(427144) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- sheep(101112260) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- Horse(100061688) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- domestic cat(101090328) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- cow(523962) mitogen-activated protein kinase kinase kinase 1
- Domestic Rabbit(100328655) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- naked mole-rat(101720769) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
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Antibodies
货号
说明
物种反应性
应用
Anti-MAP3K1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
Monoclonal Anti-MAP3K1 antibody produced in mouse, clone 2F6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
proximity ligation assay
western blot
proximity ligation assay
western blot
Anti-MAP3K1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-phospho-MAP3K1 (pThr1402) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MEKKK 1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
western blot
western blot
Small Molecule - Inhibitor
Proteins
货号
说明
物种
MEKK1 (900-1748)，有源，GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human