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Merck
CN

FGR

feline Gardner-Rasheed sarcoma viral oncogene homolog

别名:
SRC2, c-fgr, c-src2, p55-Fgr, p55c-fgr, p58-Fgr, p58c-fgr
物种:
Human FGR (2268), Mouse Fgr (14191), Rat Fgr (79113), domestic cat FGR (101083781), dog FGR (487341), sheep FGR (101107075), cow FGR (516133), Horse FGR (100056804), naked mole-rat Fgr (101704214), domestic guinea pig Fgr (100735748)
UniProtKB ID:
P09769, D3DPL7, Q9UIQ3
基因ID:
  • Human(2268) Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(14191) Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog
  • Rat(79113) feline Gardner-Rasheed sarcoma viral oncogene
  • domestic cat(101083781) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • dog(487341) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • sheep(101107075) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • cow(516133) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • Horse(100056804) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • naked mole-rat(101704214) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
  • domestic guinea pig(100735748) Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog

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ELISA

货号
说明
物种
RAB0963
磷酸酪氨酸FGR /酪氨酸蛋白激酶Fgr ELISA试剂盒, ,
物种
human

Antibodies

货号
说明
物种反应性
应用
HPA002024
Anti-FGR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
WH0002268M1
Monoclonal Anti-FGR antibody produced in mouse, clone 3G10, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
MABS1140
Anti-Fgr Antibody, clone SuGr-7 14F3, clone SuGr-7 14F3, from mouse,
物种反应性
human
应用
western blot
SAB2500396
Anti-FGR antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
western blot
SAB1405811
Anti-FGR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
SML2589
达沙替尼, ≥98% (HPLC),
物种
human
CDS023389
达沙替尼, ,
物种
human

Proteins

货号
说明
物种
F8055
FGR, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EMU070111
MISSION® esiRNA, targeting mouse Fgr,
物种
mouse
EHU056441
MISSION® esiRNA, targeting human FGR,
物种
human