CARD8
caspase recruitment domain family, member 8
别名:
CARDINAL, DACAR, DAKAR, NDPP, NDPP1, TUCAN
物种:
UniProtKB ID:
基因ID:
- Human(22900) Summary: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
- dog(491519) caspase recruitment domain family, member 8
- domestic cat(101093817) caspase recruitment domain family, member 8
- chicken(416998) caspase recruitment domain family, member 8
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-CARD8 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CARD8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CARD8 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunocytochemistry
immunofluorescence
western blot
immunocytochemistry
immunofluorescence
western blot
Anti-CARD8 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-CARD8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry
esiRNA
货号
说明
物种
Small Molecule - Substrate
货号
说明
物种