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  • Taxonomically Restricted Genes with Essential Functions Frequently Play Roles in Chromosome Segregation in

Taxonomically Restricted Genes with Essential Functions Frequently Play Roles in Chromosome Segregation in

G3 (Bethesda, Md.) (2017-08-26)
Adrian J Verster, Erin B Styles, Abigail Mateo, W Brent Derry, Brenda J Andrews, Andrew G Fraser
ABSTRACT

Genes encoding essential components of core cellular processes are typically highly conserved across eukaryotes. However, a small proportion of essential genes are highly taxonomically restricted; there appear to be no similar genes outside the genomes of highly related species. What are the functions of these poorly characterized taxonomically restricted genes (TRGs)? Systematic screens in