High glucose stimulates expression of aldosterone synthase (

High glucose stimulates expression of aldosterone synthase (

FEBS open bio (2017-09-15)

Hiroki Shimada, Naotaka Kogure, Erika Noro, Masataka Kudo, Kaori Sugawara, Ikuko Sato, Kyoko Shimizu, Makoto Kobayashi, Dai Suzuki, Rehana Parvin, Takako Saito-Ito, Akira Uruno, Akiko Saito-Hakoda, William E Rainey, Sadayoshi Ito, Atsushi Yokoyama, Akira Sugawara

PMID28904869

ABSTRACT

Aldosterone synthase is the key rate-limiting enzyme in adrenal aldosterone production, and induction of its gene (

MATERIALS

Product Number

Brand

Product Description

SML1394

Sigma-Aldrich

Olmesartan, ≥98% (HPLC)

EHU008731

Sigma-Aldrich

MISSION^® esiRNA, targeting human NR4A2

G5500

Sigma-Aldrich

L-(−)-Glucose, ≥99%

E0159

Sigma-Aldrich

Efonidipine hydrochloride monoethanolate, ≥98% (HPLC)