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CD44

Journal of cellular and molecular medicine (2017-05-20)
Yonglei Liu, Conghui Yu, Yonggang Wu, Xiangjun Sun, Quanping Su, Cuiping You, Hongwu Xin
ABSTRACT

CD44, a cell adhesion protein, involves in various process in cancer such as cell survival and metastasis. Most researches on CD44 in cancer focus on cancer cells. Recently, it is found that CD44 expression is high in fibroblasts of tumour microenvironment. However, its role in communication between fibroblasts and breast cancer cells is seldom known. In this study, CD44-positive (CD44

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MISSION® esiRNA, targeting human IGF2BP3