- Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function.
Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function.
Journal of leukocyte biology (2016-09-08)
Sorim Nam, Kyeongah Kang, Jae Seon Cha, Jung Woo Kim, Hee Gu Lee, Yonghwan Kim, Young Yang, Myeong-Sok Lee, Jong-Seok Lim
PMID27601624
ABSTRACT
Myeloid-derived suppressor cells (MDSCs) are immature cells that do not differentiate into mature myeloid cells. Two major populations of PMN-MDSCs (Ly6G