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  • A cyclopropanol-based strategy for subunit coupling: total synthesis of (+)-spirolaxine methyl ether.

A cyclopropanol-based strategy for subunit coupling: total synthesis of (+)-spirolaxine methyl ether.

Organic letters (2007-06-15)
Katie A Keaton, Andrew J Phillips
ABSTRACT

A strategy for ketone synthesis with cyclopropanols as intermediates and its application to (+)-spirolaxine methyl ether is described. The synthesis also features an application of Fu's alkyl-alkyl Suzuki coupling.

MATERIALS
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Product Description

Sigma-Aldrich
3,5-Dimethoxybenzaldehyde, 98%