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  • ipso-nitration of arylboronic acids with chlorotrimethylsilane-nitrate salts.

ipso-nitration of arylboronic acids with chlorotrimethylsilane-nitrate salts.

Organic letters (2004-06-18)
G K Surya Prakash, Chiradeep Panja, Thomas Mathew, Vijayalakshmi Surampudi, Nicos A Petasis, George A Olah
ABSTRACT

[reaction: see text] A mixture of nitrate salt and chlorotrimethylsilane is found to be an efficient regioselective nitrating agent for the ipso-nitration of arylboronic acids to produce the corresponding nitroarenes in moderate to excellent yields. High selectivity, simplicity, and convenience are the key features of the reaction.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
3-Bromophenylboronic acid, ≥95%