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  • Direct and practical synthesis of 2-arylbenzoxazoles promoted by activated carbon.

Direct and practical synthesis of 2-arylbenzoxazoles promoted by activated carbon.

Organic letters (2003-09-26)
Yuka Kawashita, Natsuki Nakamichi, Hirotoshi Kawabata, Masahiko Hayashi
ABSTRACT

[reaction: see text] 2-Arylbenzoxazoles were directly synthesized from substituted 2-aminophenols and aldehydes in the presence of activated carbon (Darco KB) in xylene under an oxygen atmosphere.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
2-Aminophenol, 99%
Sigma-Aldrich
Activated charcoal, DARCO®, 4-12 mesh particle size, granular
Sigma-Aldrich
Activated charcoal, DARCO®, 12-20 mesh, granular