CuCl2-catalyzed one-pot formation of tetrahydroquinolines from N-methyl-N-alkylanilines and vinyl ethers in the presence of t-butylhydroperoxide.

CuCl2-catalyzed one-pot formation of tetrahydroquinolines from N-methyl-N-alkylanilines and vinyl ethers in the presence of t-butylhydroperoxide.

Molecules (Basel, Switzerland) (2007-11-17)

Xianghua Yang, Chanjuan Xi, Yanfeng Jiang

ABSTRACT

Tetrahydroquinoline skeletons can be formed by a CuCl2-catalyzed one-pot reaction of N-methyl-N-alkylanilines and vinyl ethers in the presence of t-butyl-hydroperoxide.

MATERIALS

Product Number

Brand

Product Description

41690

Sigma-Aldrich

4,N,N-Trimethylaniline, catalyst grade (for peroxide polymerization), ≥98.5% (GC)

41700

Sigma-Aldrich

4,N,N-Trimethylaniline, purum, ≥98.0% (GC)