- Synthesis of C1-C20 and C21-C40 fragments of tetrafibricin.
Synthesis of C1-C20 and C21-C40 fragments of tetrafibricin.
Tetrahedron letters (2011-05-24)
Venugopal Gudipati, Dennis P Curran
PMID21603053
ABSTRACT
Efficient syntheses of suitably functionalized top and bottom fragments of tetrafibricin are described. The bottom fragment is prepared by two consecutive Kocienski-Julia couplings, while the top fragment synthesis features a dithiane alkylation and a Horner-Wadsworth-Emmons reaction.
MATERIALS