FluoMar, a fluorous version of the Marshall resin for solution-phase library synthesis.

[structure: see text] The fluorous counterpart of the Marshall resin, 4-(1H,1H,2H,2H-perfluorodecylsulfanyl)phenol (FluoMar), is prepared by S-alkylation of 4-mercaptophenol with C(8)F(17)CH(2)CH(2)I and employed in the synthesis of amide and diamide analogues. The final products are purified by solid-phase extraction (SPE) over FluoroFlash silica cartridges.