Cell biology of molybdenum.

Cell biology of molybdenum.

BioFactors (Oxford, England) (2009-07-23)

Ralf R Mendel

PMID19623604

ABSTRACT

The transition element molybdenum (Mo) is an essential micronutrient that is needed as catalytically active metal during enzyme catalysis. In humans four enzymes depend on Mo: sulfite oxidase, xanthine oxidoreductase, aldehyde oxidase, and mitochondrial amidoxime reductase. In addition to these enzymes, plants harbor a fifth Mo-enzyme namely nitrate reductase. To gain biological activity and fulfill its function in enzymes, Mo has to be complexed by a pterin compound thus forming the molybdenum cofactor. This article will review the way that Mo takes from uptake into the cell, via formation of the molybdenum cofactor and its storage, up to the final insertion of the molybdenum cofactor into apometalloenzymes.

MATERIALS

Product Number

Brand

Product Description

366986

Sigma-Aldrich

Molybdenum, powder, 10 μm, ≥99.95% trace metals basis

203823

Sigma-Aldrich

Molybdenum, powder, <150 μm, 99.99% trace metals basis

577987

Sigma-Aldrich

Molybdenum, nanopowder, <100 nm particle size (TEM), 99.8% trace metals basis

357227

Sigma-Aldrich

Molybdenum, foil, thickness 0.025 mm, ≥99.9% trace metals basis

266922

Sigma-Aldrich

Molybdenum, foil, thickness 0.1 mm, ≥99.9% trace metals basis

357200

Sigma-Aldrich

Molybdenum, foil, thickness 1.0 mm, ≥99.9% trace metals basis

266892

Sigma-Aldrich

Molybdenum, powder, <150 μm, 99.9% trace metals basis

510092

Sigma-Aldrich

Molybdenum, powder, 1-5 μm, ≥99.9% trace metals basis

GF61121304

Molybdenum, foil, not light tested, 100x100mm, thickness 0.007mm, 99.9%

GF27269635

Molybdenum, rod, 50mm, diameter 25mm, centerless ground, 99.9%

GF62673846

Molybdenum, foil, not light tested, 100x100mm, thickness 0.006mm, 99.9%

GF87605040

Molybdenum, foil, light tested, 25x25mm, thickness 0.009mm, 99.9%

GF37855974

Molybdenum, foil, light tested, 29x200mm, thickness 0.0712mm, annealed, 99.9%

GF11002149

Molybdenum, foil, not light tested, 100x100mm, thickness 0.01mm, 99.9%

GF48963549

Molybdenum, foil, light tested, 50x50mm, thickness 0.006mm, 99.9%

GF30779208

Molybdenum, rod, 500mm, diameter 1.25mm, centerless ground, 99.9%

GF12034178

Molybdenum, pellets, 100g, max. size 10mm, 99.9%

GF83989939

Molybdenum, foil, 1m coil, thickness 0.04mm, coil width 0.7mm, annealed, 99.9%

GF94111129

Molybdenum, foil, 15mm disks, thickness 0.025mm, annealed, 99.9%

GF86027957

Molybdenum, foil, 10mm disks, thickness 0.01mm, 99.9%

GF24748454

Molybdenum, foil, 4mm disks, thickness 0.005mm, 99.9%

GF18641022

Molybdenum, foil, 6mm disks, thickness 0.006mm, 99.9%

GF07368026

Molybdenum, foil, 4mm disks, thickness 0.30mm, annealed, 99.9%

GF23017216

Molybdenum, foil, 6mm disks, thickness 0.025mm, annealed, 99.9%

GF15340306

Molybdenum, foil, 6mm disks, thickness 0.007mm, 99.9%

GF45968877

Molybdenum, foil, 6mm disks, thickness 0.03mm, annealed, 99.9%

GF40348065

Molybdenum, foil, 6mm disks, thickness 0.020mm, annealed, 99.9%

GF68872078

Molybdenum, foil, 4mm disks, thickness 0.020mm, annealed, 99.9%

GF64762140

Molybdenum, foil, 50mm disks, thickness 0.25mm, annealed, 99.9%

GF75235989

Molybdenum, foil, 6mm disks, thickness 0.0125mm, 99.9%