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  • Synthesis of an array of potential matrix metalloproteinase inhibitors using a sequence of polymer-supported reagents.

Synthesis of an array of potential matrix metalloproteinase inhibitors using a sequence of polymer-supported reagents.

Bioorganic & medicinal chemistry letters (1999-08-18)
M Caldarelli, J Habermann, S V Ley
PMID10450979
ABSTRACT

Polymer-supported reagents and sequestering agents may be used to generate an array of variously substituted hydroxamic acid derivatives as potential inhibitors of matrix metalloproteinases without any chromatographic purification step.