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Merck
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Copper-mediated trifluoromethylthiolation of α-diazoesters.

Organic letters (2014-03-26)
Mingyou Hu, Jian Rong, Wenjun Miao, Chuanfa Ni, Yongxin Han, Jinbo Hu
PMID24660960
ABSTRACT

A novel Cu-mediated trifluoromethylthiolation of diazo compounds has been developed that provides a convenient synthetic route for the efficient α-trifluoromethylthiolation of simple esters under mild reaction conditions. The reaction is typically carried out at room temperature, and water could be used to promote the reaction.

MATERIALS
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