Skip to Content
Merck
CN
  • Measurement of aromatisation by a urine technique suitable for the evaluation of aromatase inhibitors in vivo.

Measurement of aromatisation by a urine technique suitable for the evaluation of aromatase inhibitors in vivo.

Journal of enzyme inhibition (1991-01-01)
S Jacobs, P E Lønning, B Haynes, L Griggs, M Dowsett
ABSTRACT

By modification of a recently developed method for separation of radio-labelled urinary oestrogens we were able to separate oestrogen metabolites and measure their isotope ratios in urine following injections of [3H]delta 4-androstenedione and [14C]oestrone. This method provides a useful tool for studying in vivo aromatisation of delta 4-androstenedione into oestrone in breast cancer patients before and during treatment with aromatase inhibitors.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
β-Glucuronidase from Helix pomatia, Type H-3, aqueous solution, ≥90,000 units/mL
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 L
In Stock
Details...
¥502.91
1 kg
In Stock
Details...
¥629.17
2.5 L
In Stock
Details...
¥877.35
25 L
Please contact Customer Service for Availability
¥5,357.74
17 kg
Please contact Customer Service for Availability
¥7,649.30