- Conjugate addition of lithiated methyl pyridines to enones.
Conjugate addition of lithiated methyl pyridines to enones.
The Journal of organic chemistry (2010-08-14)
Douglass F Taber, Pengfei Guo, Michael T Pirnot
PMID20704446
ABSTRACT
Preparatively useful conjugate addition of lithiated methyl pyridines to cyclic and acyclic enones is reported. Addition of 2-picoline to 3-penten-2-one led to a concise synthesis of the alkaloids (+/-)-senepodine G and (+/-)-cermizine C.
MATERIALS