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  • The occurrence of 2-hydroxyisovaleric acid in patients with lactic acidosis and ketoacidosis.

The occurrence of 2-hydroxyisovaleric acid in patients with lactic acidosis and ketoacidosis.

Clinica chimica acta; international journal of clinical chemistry (1977-08-01)
S Landaas, C Jakobs
PMID884872
ABSTRACT

Examination of urine samples by capillary column gas chromatography and mass spectrometry showed the presence of 2-hydroxyisovaleric acid together with trace amounts of the three branched-chain 2-keto acids in five patients with lactic and ketoacidosis. None of these compounds was detected in urine from healthy controls.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
2-Hydroxy-3-methylbutyric acid, 99%