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  • Green method for the synthesis of highly substituted cyclohexa-1,3-diene, polyhydroindene, polyhydronaphthalene, isochromene, isothiochromene, and isoquinoline derivatives in ionic liquids.

Green method for the synthesis of highly substituted cyclohexa-1,3-diene, polyhydroindene, polyhydronaphthalene, isochromene, isothiochromene, and isoquinoline derivatives in ionic liquids.

Journal of combinatorial chemistry (2009-09-22)
Xiang-Shan Wang, Jian-Rong Wu, Jie Zhou, Shu-Jiang Tu
ABSTRACT

An efficient and green method for the synthesis of highly substituted cyclohexa-1,3-diene, polyhydroindene, polyhydronaphthalene, isochromene, isothiochromene, and isoquinoline derivatives has been developed. The synthesis was achieved by using a multicomponent procedure in ionic liquid media. The features of this procedure are characterized by the following: mild reaction conditions, high yields, one-pot procedures, operational simplicity, and environmentally benign conditions.

MATERIALS
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Product Description

Sigma-Aldrich
1,3-Cyclohexadiene, contains 0.05% BHT as inhibitor, 97%