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  • D-lactate dehydrogenase. Substrate specificity and use as a catalyst in the synthesis of homochiral 2-hydroxy acids.

D-lactate dehydrogenase. Substrate specificity and use as a catalyst in the synthesis of homochiral 2-hydroxy acids.

Applied biochemistry and biotechnology (1989-11-01)
E S Simon, R Plante, G M Whitesides
ABSTRACT

This note compares the substrate specificity of D-lactate dehydrogenase (D-LDH, EC 1.1.1.28) to that of L-lactate dehydrogenase (L-LDH, EC 1.1.1.27), illustrates three procedures that use D-LDH in synthesis and two methods for recycling NADH, and provides experimental details illustrating the use of D-LDH in organic synthesis.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
1,2-Epoxybutane, 99%
Sigma-Aldrich
(S)-(−)-1,2-Epoxybutane, 98%
Sigma-Aldrich
(R)-(+)-1,2-Epoxybutane, 98%