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  • [Protection of 2'-hydroxyls in the chemical synthesis of oligoribonucleotides].

[Protection of 2'-hydroxyls in the chemical synthesis of oligoribonucleotides].

Bioorganicheskaia khimiia (2013-07-13)
A V Aralov, O G Chakhmakhchieva
ABSTRACT

The review is devoted to the chemical synthesis of oligoribonucleotides and the protecting groups used. In particular the existent methods of blocking 2'-OH function in nucleotide monomers for the RNA synthesis are discussed in detail.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Ribonucleic acid from torula yeast, core, Type II-C
Sigma-Aldrich
Ribonucleic acid from torula yeast, Type VI
Sigma-Aldrich
Ribonucleic acid from baker′s yeast (S. cerevisiae)
Sigma-Aldrich
Ribonucleic acid diethylaminoethanol salt, Type IX