- Conformational modulation of Ant-Pro oligomers using chirality alteration of proline residues.
Conformational modulation of Ant-Pro oligomers using chirality alteration of proline residues.
Organic & biomolecular chemistry (2012-09-25)
Sangram S Kale, Amol S Kotmale, Achintya Kumar Dutta, Sourav Pal, P R Rajamohanan, Gangadhar J Sanjayan
PMID23001178
ABSTRACT
Structural modulation of Ant-Pro (anthranilic acid-proline) oligomers has been carried out by chirality alteration of the proline residues. The results suggest that the chirality altered oligomers show well-defined helical conformation featuring nine-membered hydrogen bonding interactions - without compromising conformational rigidity.