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  • Highly stereoselective synthesis of cis-β-enaminones mediated by diethyl azodicarboxylate.

Highly stereoselective synthesis of cis-β-enaminones mediated by diethyl azodicarboxylate.

Chemical communications (Cambridge, England) (2012-01-06)
Xiaoliang Xu, Ping Du, Dongping Cheng, Hong Wang, Xiaonian Li
ABSTRACT

Promoted by diethyl azodicarboxylate, a novel and highly stereoselective synthesis of cis-β-enaminones via oxidative dehydrogenation and hydration of the substituted propargylamines was realized. The possible mechanism was also proposed.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Propargylamine, 98%
Sigma-Aldrich
Propargylamine hydrochloride, 95%