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  • Ginkgo biloba extract alters the binding of the sodium [123I] iodide (Na123I) on blood constituents.

Ginkgo biloba extract alters the binding of the sodium [123I] iodide (Na123I) on blood constituents.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine (2011-09-20)
Luiz Cláudio Martins Aleixo, Silvana Ramos Farias Moreno, Rosimeire de Souza Freitas, Hélio Thomaz, Sebastião David Santos-Filho, Mario Bernardo-Filho
ABSTRACT

We evaluated the in vitro effect of an aqueous extract of Ginkgo biloba (EGb) on the distribution in blood cells (BC) and plasma (P) and on the binding of Na(123)I to the blood constituents using precipitation with trichloroacetic acid. The radioactivity percentages insoluble (SF) and insoluble fraction (IF) of blood constituents were determined. The EGb interfered (p<0.05) on the distribution of Na(123)I in the P (from 69.64 to 86.13) and BC (from 30.36 to 13.87) and altered the fixation of the Na(123)I in IF-P and in IF-BC.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Sodium iodide, ReagentPlus®, ≥99%
Sigma-Aldrich
Sodium iodide, puriss., meets analytical specification of Ph. Eur., BP, USP, 99-100.5% (calc. to the dried substance)
Sigma-Aldrich
Sodium iodide, ACS reagent, ≥99.5%
Sigma-Aldrich
Sodium iodide, 99.999% trace metals basis
Sigma-Aldrich
Sodium iodide, AnhydroBeads, −10 mesh, 99.999% trace metals basis
Sigma-Aldrich
Sodium iodide, ≥99.99% trace metals basis