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  • Poly(2,3-diaminonaphthalene) microspheres as a novel quencher for fluorescence-enhanced nucleic acid detection.

Poly(2,3-diaminonaphthalene) microspheres as a novel quencher for fluorescence-enhanced nucleic acid detection.

The Analyst (2011-04-01)
Jingqi Tian, Yingwei Zhang, Yonglan Luo, Hailong Li, Junfeng Zhai, Xuping Sun
ABSTRACT

In this Communication, we report on the first preparation of conjugation polymer poly(2,3-diaminonaphthalene) (PDAN) microspheres via chemical oxidation polymerization of 2,3-diaminonaphthalene (DAN) monomers by ammonium persulfate (APS) at room temperature. We further demonstrate the use of PDAN microspheres as a novel quencher for fluorescence-enhanced nucleic acid detection.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
2,3-Diaminonaphthalene, BioReagent, suitable for fluorescence, ≥98.0% (HPLC)
Sigma-Aldrich
2,3-Diaminonaphthalene, ≥95% (HPLC), powder