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  • Lithium pipecolinate as a facile and efficient ligand for copper-catalyzed hydroxylation of aryl halides in water.

Lithium pipecolinate as a facile and efficient ligand for copper-catalyzed hydroxylation of aryl halides in water.

Chemical communications (Cambridge, England) (2010-05-22)
Linhai Jing, Jiangtao Wei, Li Zhou, Zhiyong Huang, Zhengkai Li, Xiangge Zhou
ABSTRACT

Direct hydroxylation of a wide scope of aryl halides was catalyzed by a combination of CuI and lithium pipecolinate in water with yields up to 92%.

MATERIALS
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Sigma-Aldrich
Iodobenzene, 98%