- One-pot, Pd-catalyzed synthesis of trans-dihydrobenzofurans from o-aminophenols.
One-pot, Pd-catalyzed synthesis of trans-dihydrobenzofurans from o-aminophenols.
Organic letters (2010-03-27)
Ericsson D Coy, Ljubisa Jovanovic, Michael Sefkow
PMID20337490
ABSTRACT
An efficient and facile synthesis of trans-dihydrobenzofurans has been accomplished from o-aminophenols and phenylpropenes via a novel (one-pot) diastereoselective Pd-catalyzed oxyarylation reaction. The development and optimization of this method is described.
MATERIALS