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  • Tandem Knoevenagel-Michael addition of aryl sulfonimines with diethyl malonate for synthesis of arylidene dimalonates.

Tandem Knoevenagel-Michael addition of aryl sulfonimines with diethyl malonate for synthesis of arylidene dimalonates.

The Journal of organic chemistry (2007-06-26)
Renhua Fan, Weizi Wang, Dongming Pu, Jie Wu
ABSTRACT

A highly efficient, one-flask tandem Knoevenagel-Michael addition reaction of sulfonimines with diethyl malonate in the presence of a catalytic amount of base affords the corresponding arylidene dimalonates in good to excellent yields.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Diethyl malonate, ≥98%, FG
Sigma-Aldrich
Diethyl malonate, ReagentPlus®, 99%